UofA Dentistry Students Research Day - University of Alberta
Here are the pics taken on March 31, 2006 for UAlberta dental school student research day.
UofA Dentistry Student Research Day 2006 Poster Presentation
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Here are the pics taken on March 31, 2006 for UAlberta dental school student research day.
UofA Dentistry Student Research Day 2006 Poster Presentation
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Here is the plaque I received for being the second place in the junior category of CADR-IMHA Student Research Awards Competition.
I did this research project with Dr. Mark Darling and Dr. Tom Daley at University of Western Ontario (UWO). Both supervisors are Oral Pathologists. The research was funded by Network for Oral Research Training & Health (NORTH) and National Organization for Rare Disorders (NORD).
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Today is the Research Day at University of Alberta Dentistry where dentistry and dental hygiene students present their research in the poster format. This year UAlberta Dentistry Student Research Day was held in Snell Hall inside UofA hospital. There was one poster from second year dentistry student and one poster from third year (that’s me.
). All the others are from fourth year dentistry and third year dental hygiene.
Below is my poster. I did my research in the summer of 2005 at University of Western Ontario with two oral pathologists, Drs. Mark Darling and Tom Daley. The research was funded by NORTH dental research. Click to enlarge it.

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This is Part 4 of the Niagara Falls Canada trip. Here are part 1, part 2 and part 3. The following photos were taken on Wednesday, August 25, 2005—my last third day at UWO (University of Western Ontario) for my NORTH dental research.
White Water Walk isn’t as a nice walk as I expected. Nothing extraordinary, I guess. To get down to near the river, you’ll have to take an old elevator in a souvenir shop, and then pass through a tunnel to the riverside. The line-up was pretty long in both up and down directions, since there was only one elevator operating. Waiting outside the shop for going down and then waiting in the tunnel for going up was simply taking too much time. I probably spent 1 hour just for waiting in the line-up and 10min for the White Water Walk itself. The trail is short as you can imagine.
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NORTH Dental Research starts its online e-conference today. NORTH stands for Network for Oral Research Training and Health. Below is the research project I did with two oral pathologists—Dr. Mark Darling and Dr. Tom Daley—at the University of Western Ontario (UWO), London, Ontario during summer 2005. Have a look.
My research was awarded 2nd place in the Junior Category of 2005-06 CADR-IMHA Student Research Awards Competition.

Background: Human tissue kallikreins (hKs) comprise 15 extracellular serine proteases secreted by various tissues. hKs are associated with malignancies such as prostate, breast, ovarian and testicular cancers, where hK expression levels are altered and represent prognostic factors. PCR analyses show that normal salivary glands express several hKs, but their physiological roles remain unknown.
Objective: This study investigated the expression levels of hK5 and hK8 in normal salivary glands, pleomorphic adenoma (PA), mucoepidermoid carcinoma (MEC), adenoid cystic carcinoma (ACC), polymorphous low grade adenocarcinoma (PLGA), acinic cell adenocarcinoma (ACI), and adenocarcinoma not otherwise specified (ANOS).
Method: Formalin-fixed paraffin-embedded human salivary gland tissues and tumors were evaluated by avidin:biotinylated-horseradish-peroxidase immunohistochemistry with appropriate positive and negative controls. Immunostaining signal was evaluated by two separate examiners and expressed as the sum of scores representing the proportion and staining intensity of cell cytoplasm (ranges 0-5 and 0-3, respectively).
Results: hK5 is absent in normal glands and most tumor cells, but present in keratin-producing epithelia of PA. hK8 is present in normal and all tumor tissues, with preferential expression in ductal cells. This trend is significant in normal glands (p<0.01, n=67) and PA (p<0.01, n=21), but not in ACC and PLGA. In MEC, intermediate cells have the highest hK8 expression, followed by squamous cells and then mucous cells (p≤0.04, n=22).
Conclusions: hK5 is associated with keratinized epithelia; however, its limited expression in normal and tumor tissues renders little value to diagnostic or prognostic application. hK8’s widespread expression, not specific to the tumors, cannot be used as a diagnostic marker to differentiate such tumors. However, its presence allows future investigation about whether its expression in each tumor will change in relation to cancer staging and grading—an important prognostic aspect for treatment planning and management of cancer patient after a diagnosis is established.
Key words: human kallikreins, hK, salivary gland tumors, immunohistochemistry
Source: http://www.northdentalresearch.ca/eConference/st7/index.pdf
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